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FOXO4-DRI
Molecular Formula:CA228HA388NA86OA64;CAS:2460055‑10‑9Basic Property:D‑retro‑inverso synthetic senolytic peptide for selective senescent cell clearance in longevity mechanism research.Structural Modification:All‑D‑amino‑acid reversed sequence greatly improves protease resistance; competitively binds p53 to block endogenous FOXO4‑p53 interaction.Dosage Forms:Sterile lyophilized powder for animal local injection research only.Indications:Preclinical research on clearing senescent cells, relieving chronic sterile inflammation and delaying tissue aging.Pharmacological Mechanism:Induces mitochondrial translocation of p53 exclusively in senescent cells to trigger targeted apoptosis without damaging healthy cells.Safety & Adverse Reactions:Transient mild inflammatory response after high‑dose administration in animal models; human clinical safety data is insufficient at present.
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