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Gonadorelin
Molecular Formula:CA55HA75NA17OA13;CAS:33515‑09‑2Basic Property:Natural synthetic decapeptide identical to endogenous hypothalamic GnRH for reproductive endocrine rhythm research.Structural Modification:Native peptide structure with short half‑life, suitable for simulating physiological pulsatile administration mode.Dosage Forms:Lyophilized powder for animal injection / pump pulsatile administration experiments.Indications:Preclinical research on hypothalamic amenorrhea, ovulation induction and pituitary gonadotroph function detection.Pharmacological Mechanism:Periodic binding to pituitary GnRH receptors promotes pulsatile secretion of LH and FSH to maintain normal gonadal function.Safety & Adverse Reactions:Continuous high‑dose administration induces receptor desensitization and temporary reproductive axis inhibition in animal trials.
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